SCHEMBL24800805

SCHEMBL24800805

NC(=O)Cn1cc(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.50
▸ TP53 P04637 3/20 0.50
▸ MDM2 Q00987 6/20 0.44
▸ SLC17A5 Q9NRA2 1/20 0.43
▸ CASP3 P42574 2/20 0.42
▸ KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26008959 0.91 MDM4 (0.50) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL9113360 0.89 MDM4 (0.52) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL29160941 0.89 MDM4 (0.48) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL29160943 0.89 MDM4 (0.48) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL31370341 0.88 MDM4 (0.51) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL849963 0.88 MDM4 (0.51) MDM4TP53MDM2SLC17A5
SCHEMBL32664869 0.87 MDM4 (0.48) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL30002165 0.87 MDM4 (0.48) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL16100700 0.87 MDM4 (0.48) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL30959635 0.87 MDM4 (0.48) MDM4TP53MDM2SLC17A5CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203098-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE JCR PHARMACEUTICALS CO., LTD. (JP) 2023-06-29 — — US disclosed
EP-4108676-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE JCR Pharmaceuticals Co., Ltd. (JP) 2022-12-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203098-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE TFRC, SLC3A2, SLC7A1 MDM4 4269/4885TP53 2445/4885MDM2 4069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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