Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.56 |
| ▸ | KRAS | P01116 | 5/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.53 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737039 | 0.86 | KDM4E (0.62) | TNFRSF1AMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10737031 | 0.86 | KDM4E (0.62) | TNFRSF1AMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2744009 | 0.84 | TNFRSF1A (0.60) | TNFRSF1AABCB1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29045031 | 0.83 | MAPT (0.57) | TNFRSF1AABCB1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL16171985 | 0.82 | MAPT (0.67) | TNFRSF1AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL11796150 | 0.81 | ABCB1 (0.83) | TNFRSF1AABCB1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11796142 | 0.81 | ABCB1 (0.83) | TNFRSF1AABCB1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9113586 | 0.81 | ABCB1 (0.56) | TNFRSF1AABCB1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9113609 | 0.81 | ABCB1 (0.56) | TNFRSF1AABCB1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9672672 | 0.80 | TNFRSF1A (0.52) | TNFRSF1AABCB1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | disclosed |