SCHEMBL16171985

SCHEMBL16171985

COCCOCOc1ccc(/C=C/C(=O)c2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.67
KMT2A Q03164 2/20 0.67
NPC1 O15118 1/20 0.67
RAB9A P51151 1/20 0.67
BCHE P06276 7/20 0.64
CYP3A4 P08684 1/20 0.64
NFKB1 P19838 1/20 0.64
NFKB2 Q00653 1/20 0.64
RELA Q04206 1/20 0.64
MAOB P27338 5/20 0.60
MAOA P21397 1/20 0.60
ACHE P22303 6/20 0.57
MEN1 O00255 1/20 0.57
ALDH1A1 P00352 1/20 0.57
HSPD1 P10809 1/20 0.57
TNFRSF1A P19438 1/20 0.57
HSPE1 P61604 1/20 0.57
CYP1B1 Q16678 1/20 0.57
ABCG2 Q9UNQ0 1/20 0.55
PPARA Q07869 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16171984 0.91 NPC1 (0.63) MAPTKMT2ANPC1RAB9ABCHE
SCHEMBL25238725 0.91 XDH (0.65) MAPTKMT2ANPC1RAB9AMAOB
SCHEMBL13223567 0.89 MAPT (0.74) MAPTKMT2ANPC1RAB9ABCHE
SCHEMBL12062067 0.87 MAPT (0.67) MAPTKMT2ANPC1RAB9ABCHE
SCHEMBL5750014 0.85 THRB (0.59) MAPTKMT2ANPC1RAB9AMAOB
SCHEMBL7663462 0.85 THRB (0.59) MAPTKMT2ANPC1RAB9AMAOB
SCHEMBL13223565 0.84 MAOB (0.74) MAPTKMT2ANPC1RAB9ABCHE
SCHEMBL12062069 0.83 MAPT (0.62) MAPTKMT2ANPC1RAB9ABCHE
SCHEMBL12062070 0.82 NPC1 (0.64) MAPTKMT2ANPC1RAB9ABCHE
SCHEMBL10477124 0.82 FDPS (0.49) MAOBABCG2PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9465244-B2 Liquid crystal display SONY CORPORATION (JP) 2016-10-11 US disclosed
US-20140307211-A1 LIQUID CRYSTAL DISPLAY SONY CORPORATION (JP) 2014-10-16 US disclosed