Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 7/20 | 0.57 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.56 |
| ▸ | CTSC | P53634 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | GHSR | Q92847 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 3/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31039961 | 0.89 | MAGI3 (0.58) | ECE1MAGI3CTSCACEERBB2 | |
| SCHEMBL30567428 | 0.88 | ACE (0.61) | ECE1MAGI3CTSCACEMMP9 | |
| SCHEMBL29750422 | 0.88 | ACE (0.67) | ECE1ACEERAP2 | |
| SCHEMBL30123268 | 0.87 | ACE (0.66) | ECE1CTSCACEERAP2 | |
| SCHEMBL9143491 | 0.87 | GHSR (0.58) | ECE1MAGI3GHSR | |
| SCHEMBL30834731 | 0.86 | ACE (0.53) | ECE1MAGI3CTSCACEMMP9 | |
| SCHEMBL19138339 | 0.84 | ECE1 (0.58) | ECE1MAGI3ACEMMP9MMP8 | |
| SCHEMBL19138342 | 0.84 | ECE1 (0.58) | ECE1MAGI3ACEMMP9MMP8 | |
| SCHEMBL24739439 | 0.84 | GHSR (0.57) | ECE1MAGI3CTSCERBB2GHSR | |
| SCHEMBL9112028 | 0.83 | UTS2R (0.62) | MAGI3ERBB2GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464935-A | Peptide inhibitors of selectin binding | CENTOCOR, INC. (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0652897-A4 | PEPTIDE INHIBITORS OF SELECTIN BINDING. | CENTOCOR INC (US) | 1995-09-20 | — | — | EP | disclosed |
| EP-0652897-A1 | PEPTIDE INHIBITORS OF SELECTIN BINDING | CENTOCOR INC. (US) | 1995-05-17 | — | — | EP | disclosed |
| WO-1993024527-A1 | PEPTIDE INHIBITORS OF SELECTIN BINDING | CENTOCOR, INC. (US) | 1993-12-09 | — | — | WO | disclosed |