Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9114302 | 1.00 | PRCP (0.36) | PRCPSLC22A1PNMTCYP2D6CYP3A4 | |
| SCHEMBL14304629 | 0.77 | PRCP (0.39) | PRCPSLC22A1PNMTKDM4EALDH1A1 | |
| SCHEMBL6066100 | 0.77 | HTR1A (0.40) | PRCPSLC22A1PNMTMEN1KMT2A | |
| SCHEMBL3111967 | 0.72 | PRCP (0.43) | PRCPSLC22A1PNMTCYP2D6CYP3A4 | |
| SCHEMBL24639493 | 0.71 | PRCP (0.42) | PRCPSLC22A1PNMTCYP2D6CYP3A4 | |
| SCHEMBL6468720 | 0.71 | PRCP (0.45) | PRCPSLC22A1PNMTALDH1A1MAPT | |
| SCHEMBL3119873 | 0.71 | HTR2A (0.47) | PRCPSLC22A1PNMTADRB2ADRB1 | |
| SCHEMBL1206939 | 0.71 | PRCP (0.42) | PRCPSLC22A1PNMTCYP2D6CYP3A4 | |
| SCHEMBL3111962 | 0.71 | PRCP (0.42) | PRCPSLC22A1PNMTCYP2D6CYP3A4 | |
| SCHEMBL1167895 | 0.71 | PRCP (0.42) | PRCPSLC22A1PNMTCYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |