Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115413 | 0.90 | TAAR1 (0.50) | TAAR1GPR84CNR1FFAR1NOS1 | |
| SCHEMBL9115392 | 0.89 | TAAR1 (0.49) | TAAR1GPR84CNR1FFAR1NOS1 | |
| SCHEMBL3906108 | 0.84 | L3MBTL1 (0.66) | TAAR1GPR84CNR1FFAR1NOS1 | |
| SCHEMBL26267889 | 0.83 | TAAR1 (0.58) | TAAR1GPR84CNR1FFAR1NOS1 | |
| SCHEMBL27858711 | 0.80 | TAAR1 (0.57) | TAAR1FFAR1SLC6A3 | |
| SCHEMBL7835625 | 0.80 | L3MBTL1 (0.70) | TAAR1FFAR1L3MBTL1KDM4EADRA2A | |
| SCHEMBL5541449 | 0.80 | TAAR1 (0.57) | TAAR1GPR84CNR1FFAR1NOS1 | |
| SCHEMBL97039 | 0.76 | NPC1 (0.61) | TAAR1CNR1 | |
| SCHEMBL6692696 | 0.74 | FFAR1 (0.67) | TAAR1FFAR1NOS1L3MBTL1 | |
| SCHEMBL3903471 | 0.74 | L3MBTL1 (0.66) | TAAR1GPR84FFAR1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648202-A1 | SUBSTITUTED (ARYLALKYLAMINOBENZYL)AMINOPROPIONAMIDE DERIVATIVES, THEIR PREPARATION AND USE ANTI-EPILEPTIC, NEUROPROTECTIVE AND ANTIDEPRESSANT AGENTS. | PHARMACIA SPA (IT) | 1995-04-19 | — | — | EP | disclosed |