Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9114434 | 1.00 | TNFRSF1A (0.54) | TNFRSF1AABCG2GABRA3GABRA2GABRB2 | |
| SCHEMBL9114006 | 0.91 | DPP4 (0.48) | ABCG2MAOBMAPTLMNASMN1; SMN2 | |
| SCHEMBL9114023 | 0.91 | DPP4 (0.48) | ABCG2MAOBMAPTLMNASMN1; SMN2 | |
| SCHEMBL9114298 | 0.90 | CAPN1 (0.46) | ABCG2MAOBDPP4PTPN1 | |
| SCHEMBL9112043 | 0.90 | CAPN1 (0.46) | ABCG2MAOBDPP4PTPN1 | |
| SCHEMBL9114929 | 0.87 | PTPN1 (0.49) | TNFRSF1AABCG2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL9114936 | 0.87 | PTPN1 (0.49) | TNFRSF1AABCG2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL9111913 | 0.87 | TNFRSF1A (0.64) | TNFRSF1AABCG2GABRA3GABRA2GABRB2 | |
| SCHEMBL9111920 | 0.87 | TNFRSF1A (0.64) | TNFRSF1AABCG2GABRA3GABRA2GABRB2 | |
| SCHEMBL9115678 | 0.86 | PTPN1 (0.56) | TNFRSF1AABCG2GABRA3GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |