Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.49 |
| ▸ | DPP4 | P27487 | 5/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9114936 | 1.00 | PTPN1 (0.49) | PTPN1DPP4ABCG2NPC1POLB | |
| SCHEMBL9111705 | 0.90 | PTPN1 (0.56) | PTPN1ABCG2FLT3TNFRSF1A | |
| SCHEMBL9111700 | 0.90 | PTPN1 (0.56) | PTPN1ABCG2FLT3TNFRSF1A | |
| SCHEMBL9114006 | 0.90 | DPP4 (0.48) | PTPN1DPP4ABCG2NPC1MAPT | |
| SCHEMBL9114023 | 0.90 | DPP4 (0.48) | PTPN1DPP4ABCG2NPC1MAPT | |
| SCHEMBL9114460 | 0.87 | KDM4E (0.49) | PTPN1ABCG2MAPTSMN1; SMN2FLT3 | |
| SCHEMBL9114455 | 0.87 | KDM4E (0.49) | PTPN1ABCG2MAPTSMN1; SMN2FLT3 | |
| SCHEMBL9114446 | 0.87 | TNFRSF1A (0.54) | PTPN1DPP4ABCG2NPC1MAPT | |
| SCHEMBL9114434 | 0.87 | TNFRSF1A (0.54) | PTPN1DPP4ABCG2NPC1MAPT | |
| SCHEMBL9112446 | 0.87 | PTPN1 (0.56) | PTPN1ABCG2FLT3TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | disclosed |