SCHEMBL9114483

SCHEMBL9114483

O=C(O)[C@H]1COC[C@H]1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 5/20 0.43
GRM4 Q14833 5/20 0.36
CYP2C19 P33261 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GRM8 O00222 2/20 0.36
GRM6 O15303 2/20 0.36
CYP2C9 P11712 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP2D6 P10635 1/20 0.36
GABRR2 P28476 1/20 0.36
SUCNR1 Q9BXA5 1/20 0.35
SLC1A2 P43004 2/20 0.35
LMNA P02545 2/20 0.33
PMP22 Q01453 2/20 0.33
KDM4E B2RXH2 2/20 0.33
APEX1 P27695 1/20 0.33
GRM5 P41594 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9114459 1.00 GABRR1 (0.43) GABRR1GRM4CYP2C19MEN1KMT2A
SCHEMBL38940 1.00 GABRR1 (0.43) GABRR1GRM4CYP2C19MEN1KMT2A
SCHEMBL9114163 0.84 GABRR1 (0.33) GABRR1GRM4CYP2C19MEN1KMT2A
SCHEMBL23110899 0.83
SCHEMBL18642165 0.83
SCHEMBL11629845 0.81
SCHEMBL638706 0.81
SCHEMBL29160138 0.81
SCHEMBL24958749 0.81
SCHEMBL6791683 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115521999-A Preparation method and application of tanning mending paste based on tanning solid waste 兴业皮革科技股份有限公司 2022-12-27 CN claimed
CN-112261970-B 3- (5-Hydroxy-1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and their use in the treatment of IKAROS family zinc finger 2 (IKZF 2) dependent diseases 诺华股份有限公司 2025-02-07 CN disclosed
CN-119241499-A 3- (5-Hydroxy-1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and uses thereof 诺华股份有限公司 2025-01-03 CN disclosed
EP-4306111-A2 3-(5-HYDROXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF Novartis AG (CH) 2024-01-17 EP disclosed
CN-115521999-A Preparation method and application of tanning mending paste based on tanning solid waste 兴业皮革科技股份有限公司 2022-12-27 CN disclosed
WO-2013095275-A1 NOVEL HEPATITIS C VIRUS INHIBITORS MEDIVIR AB (SE) 2013-06-27 WO disclosed
WO-1995007022-A1 FUNGICIDES ZENECA LIMITED (GB) 1995-03-16 WO disclosed