SCHEMBL38940

SCHEMBL38940

O=C(O)C1COCC1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 5/20 0.43
GRM4 Q14833 5/20 0.36
CYP2C19 P33261 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GRM8 O00222 2/20 0.36
GRM6 O15303 2/20 0.36
CYP2C9 P11712 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP2D6 P10635 1/20 0.36
GABRR2 P28476 1/20 0.36
SUCNR1 Q9BXA5 1/20 0.35
SLC1A2 P43004 2/20 0.35
LMNA P02545 2/20 0.33
PMP22 Q01453 2/20 0.33
KDM4E B2RXH2 2/20 0.33
APEX1 P27695 1/20 0.33
GRM5 P41594 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9114459 1.00 GABRR1 (0.43) GABRR1GRM4CYP2C19MEN1KMT2A
SCHEMBL9114483 1.00 GABRR1 (0.43) GABRR1GRM4CYP2C19MEN1KMT2A
SCHEMBL9114163 0.84 GABRR1 (0.33) GABRR1GRM4CYP2C19MEN1KMT2A
SCHEMBL23110899 0.83
SCHEMBL18642165 0.83
SCHEMBL11629845 0.81
SCHEMBL638706 0.81
SCHEMBL29160138 0.81
SCHEMBL24958749 0.81
SCHEMBL6791683 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2591040-B1 ALKYD RESIN PERSTORP AB (SE) 2019-08-14 EP claimed
EP-2591039-B1 BRANCHED POLYESTER PERSTORP AB (SE) 2018-06-13 EP claimed
EP-2591039-A1 BRANCHED POLYESTER Perstorp AB (SE) 2013-05-15 EP claimed
EP-2591040-A1 ALKYD RESIN Perstorp AB (SE) 2013-05-15 EP claimed
WO-2012005645-A1 ALKYD RESIN PERSTORP AB (SE) 2012-01-12 WO claimed
WO-2012005648-A1 UNSATURATED OLIGIO OR POLYESTER PERSTORP AB (SE) 2012-01-12 WO claimed
WO-2012005647-A1 BRANCHED POLYESTER PERSTORP AB (SE) 2012-01-12 WO claimed
CN-115521999-A Preparation method and application of tanning mending paste based on tanning solid waste 兴业皮革科技股份有限公司 2022-12-27 CN disclosed
US-11192877-B2 3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof NOVARTIS AG (CH) 2021-12-07 US disclosed
WO-2016123146-A1 BRIDGED COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS MERCK SHARP & DOHME CORP. (US) 2016-08-04 WO disclosed
WO-2016123146-A1 BRIDGED COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS MERCK SHARP & DOHME CORP. (US) 2016-08-04 WO disclosed
EP-3050888-A1 Compounds for the treatment of bacterial infections Merck Sharp & Dohme Corp. (US) 2016-08-03 EP disclosed
EP-0856025-B1 CHOLESTERIC PHASE-FORMING POLYMERS AND THEIR USE CELANESE VENTURES GMBH (DE) 2003-01-15 EP disclosed
US-6107447-A LIQUID CRYSTALLINE POLYMERS HOECHST RESEARCH TECHNOLOGY DEUTCHLAND GMBH & CO. KG (DE) 2000-08-22 US disclosed
EP-0856025-A1 CHOLESTERIC PHASE-FORMING POLYMERS, PROCESS FOR THEIR PREPARATION AND THEIR USE Hoechst Research & Technology Deutschland GmbH & Co. KG (DE) 1998-08-05 EP disclosed
WO-1997014739-A1 CHOLESTERIC PHASE-FORMING POLYMERS, PROCESS FOR THEIR PREPARATION AND THEIR USE HOECHST RESEARCH & TECHNOLOGY (DE) 1997-04-24 WO disclosed
WO-1995007022-A1 FUNGICIDES ZENECA LIMITED (GB) 1995-03-16 WO disclosed
US-5276169-A Antimycotic carbonyl- and amino-substituted tetrahydrofurans BAYER AKTIENGESELLSCHAFT (DE) 1994-01-04 US disclosed
EP-0538688-A1 Substituted tetrahydrofurans, methods for their preparation, and their use as pharmaceutical compositions BAYER AG (DE) 1993-04-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11192877-B2 3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof XDH, HTR1D, RXFP1 GABRR1 606/4885GRM4 1582/4885CYP2C19 447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.