Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | SNCA | P37840 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4158650 | 0.85 | HDAC1 (0.58) | MEN1KMT2AHDAC1MAPTKCNMA1 | |
| SCHEMBL3848169 | 0.78 | MAPT (0.67) | MEN1KMT2AHDAC1MAPTNPC1 | |
| SCHEMBL150171 | 0.78 | GPR35 (0.59) | MEN1KMT2AHDAC1SNCAMAPT | |
| SCHEMBL149937 | 0.78 | MEN1 (0.67) | MEN1KMT2AHDAC1NPC1RAB9A | |
| SCHEMBL2358357 | 0.77 | MEN1 (1.00) | MEN1KMT2AHDAC1SNCANPC1 | |
| SCHEMBL19406089 | 0.77 | MEN1 (0.56) | MEN1KMT2AHDAC1SNCAKCNMA1 | |
| SCHEMBL30739586 | 0.76 | HDAC1 (0.75) | MEN1KMT2AHDAC1NPC1RAB9A | |
| SCHEMBL30900928 | 0.76 | MEN1 (0.63) | MEN1KMT2AHDAC1MAPTNPC1 | |
| SCHEMBL30900909 | 0.76 | MEN1 (0.63) | MEN1KMT2AHDAC1MAPTNPC1 | |
| SCHEMBL30586984 | 0.76 | MEN1 (0.63) | MEN1KMT2AMAPTKCNMA1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623115-A4 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS. | DOW CHEMICAL CO (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0623115-A1 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014071-A1 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1993-07-22 | — | — | WO | disclosed |
| US-5216110-A | Monomers useful in nucleophilic displacement synthesis of polybenzazole polymers | THE DOW CHEMICAL COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| US-5194562-A | Nucleophilic displacement method for synthesis of non-rigid PBZ polymers | THE DOW CHEMICAL COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| US-5104960-A | Nucleophilic displacement method for synthesis of non-rigid PBZ polymers | THE DOW CHEMICAL COMPANY (US) | 1992-04-14 | — | — | US | disclosed |