Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402142 | 0.87 | ACACB (0.50) | PLA2G10PLA2G2ALTA4HACACBACACA | |
| SCHEMBL27296052 | 0.78 | MAOB (0.50) | SLC1A1 | |
| SCHEMBL27306471 | 0.78 | SCN9A (0.51) | ALDH1A1 | |
| SCHEMBL7399338 | 0.77 | SCN9A (0.55) | PLA2G10PLA2G2A | |
| SCHEMBL7401755 | 0.77 | SCN9A (0.55) | PLA2G10PLA2G2A | |
| SCHEMBL27328387 | 0.76 | SCN9A (0.49) | ALDH1A1 | |
| SCHEMBL9115104 | 0.76 | MAOB (0.48) | SLC1A1 | |
| SCHEMBL8935292 | 0.72 | SCN9A (0.51) | PLA2G10PLA2G2A | |
| SCHEMBL8935302 | 0.72 | SCN9A (0.51) | PLA2G10PLA2G2A | |
| SCHEMBL8935345 | 0.72 | ACACB (0.50) | PLA2G10PLA2G2ALTA4HACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449692-A | Antiepileptic, anti-Parkinson, antidepressant, antispasmodic, neuroprotective, and hypnotic agents | FARMITALIA CARLO ERBA S.R.L. (IT) | 1995-09-12 | — | — | US | disclosed |
| EP-0648202-A1 | SUBSTITUTED (ARYLALKYLAMINOBENZYL)AMINOPROPIONAMIDE DERIVATIVES, THEIR PREPARATION AND USE ANTI-EPILEPTIC, NEUROPROTECTIVE AND ANTIDEPRESSANT AGENTS. | PHARMACIA SPA (IT) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994022809-A1 | SUBSTITUTED (ARYLALKYLAMINOBENZYL)AMINOPROPIONAMIDE DERIVATIVES, THEIR PREPARATION AND USE ANTI-EPILEPTIC, NEUROPROTECTIVE AND ANTIDEPRESSANT AGENTS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1994-10-13 | — | — | WO | disclosed |