Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
| ▸ | ACACA | Q13085 | 1/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1881712 | 0.87 | APAF1 (0.59) | APAF1LMNAALDH1A1KDM4EANPEP | |
| SCHEMBL1881711 | 0.87 | APAF1 (0.59) | APAF1LMNAALDH1A1KDM4EANPEP | |
| SCHEMBL7402142 | 0.79 | ACACB (0.50) | ACACBACACAF7PLA2G10PLA2G2A | |
| SCHEMBL14149712 | 0.78 | SMN1; SMN2 (0.47) | F7LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28308274 | 0.74 | NPC1 (0.59) | LMNACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL157741 | 0.73 | APAF1 (0.62) | APAF1LMNAALDH1A1ANPEPMEN1 | |
| SCHEMBL524374 | 0.73 | APAF1 (0.62) | APAF1LMNAALDH1A1ANPEPMEN1 | |
| SCHEMBL653596 | 0.73 | APAF1 (0.62) | APAF1LMNAALDH1A1ANPEPMEN1 | |
| SCHEMBL13518285 | 0.72 | SIGMAR1 (0.58) | ACACBACACAF7PLA2G10PLA2G2A | |
| SCHEMBL7399338 | 0.72 | SCN9A (0.55) | PLA2G10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |