SCHEMBL9114517

SCHEMBL9114517

COOC(C)(OC(C)C)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL852394 0.84 TSHR (0.38) ALDH1A1TSHR
SCHEMBL9114520 0.82 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL29283321 0.81 TSHR (0.36) ALDH1A1TSHR
SCHEMBL3422574 0.69 TSHR (0.38) ALDH1A1TSHR
SCHEMBL31229139 0.66 TSHR (0.35) ALDH1A1TSHR
SCHEMBL28995292 0.65 TSHR (0.35) ALDH1A1TSHR
SCHEMBL29283320 0.65 TSHR (0.31) TSHR
SCHEMBL31331224 0.65 TSHR (0.41) ALDH1A1TSHR
SCHEMBL27472912 0.65 CYP2D6 (0.33) TSHR
SCHEMBL607413 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995012588-A1 ANTINEOPLASTIC HETERONAPHTHOQUINONES BIOCHEM PHARMA INC. (CA) 1995-05-11 WO disclosed