Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 4/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL11553348 | 0.95 | MAPT (0.53) | MAPTTDP1MEN1POLBKMT2A | |
| SCHEMBL9114376 | 0.92 | MAPT (0.58) | MAPTTDP1MEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL11553310 | 0.90 | MAPT (0.57) | MAPTTDP1MEN1POLBKMT2A | |
| SCHEMBL9827708 | 0.80 | NISCH (0.58) | MAPTMEN1POLBKMT2ANISCH | |
| SCHEMBL9114689 | 0.79 | NISCH (0.57) | TDP1MEN1KMT2ANISCHTSHR | |
| SCHEMBL3858563 | 0.78 | NISCH (0.55) | MAPTNISCHTSHRGAA | |
| SCHEMBL9023749 | 0.76 | MAPT (0.53) | MAPTTDP1MEN1POLBKMT2A | |
| SCHEMBL9043095 | 0.75 | NISCH (0.58) | TDP1MEN1KMT2ANISCHTSHR | |
| SCHEMBL1144144 | 0.75 | L3MBTL1 (0.53) | MAPTMEN1POLBKMT2ANISCH | |
| Hydrochloric Acid SCHEMBL3973011 | 0.74 | MAPT (0.92) | MAPTTDP1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995008540-A1 | BIS(AMIDINOBENZIMIDAZOLYL)ALKANES AS ANTIVIRAL AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-03-30 | — | — | WO | disclosed |