Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.65 |
| ▸ | MAOB | P27338 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112254 | 1.00 | ABCG2 (0.65) | ABCG2MAOBLMNAPOLBCYP1A1 | |
| SCHEMBL9113995 | 0.90 | ABCG2 (0.67) | ABCG2MAOBLMNAPOLBCYP1A1 | |
| SCHEMBL9112054 | 0.89 | MAPT (0.73) | ABCG2MAOBLMNAPOLBCYP1A1 | |
| SCHEMBL9112049 | 0.89 | MAPT (0.73) | ABCG2MAOBLMNAPOLBCYP1A1 | |
| SCHEMBL9112195 | 0.88 | ABCG2 (0.69) | ABCG2MAOBLMNAPOLBMAPT | |
| SCHEMBL9112439 | 0.87 | MAOB (0.70) | MAOBLMNACYP1A1CYP1A2CYP2D6 | |
| SCHEMBL9112491 | 0.86 | MAOB (0.64) | ABCG2MAOBLMNAPOLBCYP1A1 | |
| SCHEMBL9111979 | 0.86 | ABCG2 (0.61) | ABCG2MAOBLMNAPOLBCYP1A1 | |
| SCHEMBL9111984 | 0.86 | ABCG2 (0.61) | ABCG2MAOBLMNAPOLBCYP1A1 | |
| SCHEMBL11342200 | 0.85 | LMNA (0.69) | ABCG2MAOBLMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | disclosed |