Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.45 |
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29756609 | 0.88 | MEN1 (0.42) | MEN1KMT2APAK1FASNPOLB | |
| SCHEMBL23534110 | 0.88 | MEN1 (0.42) | MEN1KMT2APAK1FASNPOLB | |
| SCHEMBL5841291 | 0.80 | MEN1 (0.53) | MEN1KMT2ACYP2D6POLBMAPK1 | |
| SCHEMBL23534095 | 0.79 | POLB (0.41) | MEN1KMT2APAK1POLBMAPK1 | |
| SCHEMBL29767827 | 0.79 | POLB (0.41) | MEN1KMT2APAK1POLBMAPK1 | |
| SCHEMBL9116533 | 0.77 | CYP3A4 (0.59) | MEN1KMT2APAK1LMNAHTR1A | |
| SCHEMBL9116021 | 0.77 | MAPT (0.56) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL7324438 | 0.77 | MEN1 (0.42) | MEN1KMT2APAK1FASNPOLB | |
| SCHEMBL7411522 | 0.77 | MEN1 (0.42) | MEN1KMT2APAK1FASNPOLB | |
| SCHEMBL9117522 | 0.76 | CYP3A4 (0.58) | MEN1KMT2APAK1LMNAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025731-A1 | NOVEL 3-(φ-(4-BENZOYLPIPERIDINO)ALKYL)-4H-BENZOPYRAN-4-ONES, PREPARATION AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1995-09-28 | — | — | WO | disclosed |