Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115400 | 0.79 | TP53 (0.38) | LAP3TP53FOLH1GRIN2DGRIN3B | |
| SCHEMBL4093592 | 0.78 | FOLH1 (0.40) | FOLH1MEN1LMNAHPGDTSHR | |
| SCHEMBL10442157 | 0.77 | TP53 (0.43) | LAP3TP53FOLH1GRIN2DGRIN3B | |
| SCHEMBL7521763 | 0.77 | TP53 (0.36) | LAP3TP53FOLH1GRIN2DGRIN3B | |
| Water SCHEMBL11413207 | 0.75 | FOLH1 (0.39) | FOLH1MEN1LMNAHPGDTSHR | |
| SCHEMBL11559503 | 0.75 | TP53 (0.35) | LAP3TP53FOLH1GRIN2DGRIN3B | |
| SCHEMBL11338645 | 0.75 | TP53 (0.35) | LAP3TP53FOLH1GRIN2DGRIN3B | |
| SCHEMBL11334546 | 0.71 | FOLH1 (0.43) | FOLH1 | |
| SCHEMBL490758 | 0.71 | TP53 (0.32) | LAP3TP53FOLH1 | |
| SCHEMBL180909 | 0.70 | FOLH1 (0.36) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995011249-A1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING THEM AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-27 | — | — | WO | disclosed |