Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 3/20 | 0.53 |
| ▸ | ATP4B | P51164 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067355 | 0.84 | ATP4A (0.60) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL14290124 | 0.81 | ATP4A (0.53) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL5793857 | 0.81 | PSEN1 (0.50) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL9281843 | 0.81 | MEN1 (0.44) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL2193526 | 0.81 | ATP4A (0.63) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL9748655 | 0.81 | ATP4A (0.52) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| Iodide SCHEMBL9747433 | 0.80 | ATP4A (0.51) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL9116164 | 0.79 | TLR7 (0.46) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| Iodomethane SCHEMBL11069979 | 0.79 | ATP4A (0.50) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL182618 | 0.78 | ATP4A (0.54) | ATP4AATP4BMAPK1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459132-A | Inhibition of cell proliferation, analgesic, hypotensive | LABORATOIRES UPSA (FR) | 1995-10-17 | — | — | US | disclosed |
| WO-1995018817-A1 | NOVEL ADENOSINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRES UPSA (FR) | 1995-07-13 | — | — | WO | disclosed |