Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873178 | 1.00 | LMNA (0.52) | LMNAPOLB | |
| SCHEMBL9873430 | 1.00 | LMNA (0.52) | LMNAPOLB | |
| SCHEMBL9113426 | 1.00 | LMNA (0.52) | LMNAPOLB | |
| SCHEMBL9873057 | 1.00 | LMNA (0.52) | LMNAPOLB | |
| SCHEMBL9872933 | 1.00 | LMNA (0.52) | LMNAPOLB | |
| SCHEMBL9873666 | 1.00 | LMNA (0.52) | LMNAPOLB | |
| SCHEMBL9873092 | 0.96 | LMNA (0.56) | LMNAPOLB | |
| SCHEMBL9873695 | 0.95 | MEN1 (0.48) | LMNAPOLB | |
| SCHEMBL9872841 | 0.91 | LMNA (0.45) | LMNAPOLB | |
| SCHEMBL9872454 | 0.91 | LMNA (0.45) | LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995014679-A1 | TETRAZOLE-SUBSTITUTED UREA ACAT INHIBITORS | PARKE, DAVIS & COMPANY (US) | 1995-06-01 | — | — | WO | disclosed |
| US-5362744-A | Treatnent of athrosclerosis, anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1994-11-08 | — | — | US | disclosed |
| US-5073565-A | Atherosclerosis, anticholesterol | WARNER-LAMBERT COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| WO-1991017150-A1 | TETRAZOLE UREA AND THIOUREA ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-11-14 | — | — | WO | disclosed |