Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.58 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.57 |
| ▸ | DPP4 | P27487 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9114892 | 1.00 | ABCG2 (0.59) | ABCG2PTPN1TNFRSF1ADPP4LMNA | |
| SCHEMBL7185093 | 0.88 | DPP4 (0.58) | ABCG2PTPN1DPP4MAPTMAOB | |
| SCHEMBL7185091 | 0.88 | DPP4 (0.58) | ABCG2PTPN1DPP4MAPTMAOB | |
| SCHEMBL7192049 | 0.87 | PTPN1 (0.49) | ABCG2PTPN1DPP4LMNAMAPT | |
| SCHEMBL7192052 | 0.87 | PTPN1 (0.49) | ABCG2PTPN1DPP4LMNAMAPT | |
| SCHEMBL9113874 | 0.87 | DPP4 (0.57) | ABCG2PTPN1DPP4LMNAMAPT | |
| SCHEMBL9112642 | 0.87 | DPP4 (0.57) | ABCG2PTPN1DPP4LMNAMAPT | |
| SCHEMBL9113945 | 0.87 | PTPN1 (0.64) | ABCG2PTPN1TNFRSF1ADPP4LMNA | |
| SCHEMBL7186038 | 0.86 | CTSL (0.51) | ABCG2PTPN1DPP4LMNAMAPT | |
| SCHEMBL7186034 | 0.86 | CTSL (0.51) | ABCG2PTPN1DPP4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | disclosed |