SCHEMBL9115201

SCHEMBL9115201

Cc1c(C(=O)c2cnoc2C2CC2)ccc(Cl)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.38
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
TAS1R2 Q8TE23 1/20 0.38
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CRHR1 P34998 4/20 0.35
PDE2A O00408 1/20 0.35
HPGD P15428 3/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
SMURF2 Q9HAU4 1/20 0.34
SMURF1 Q9HCE7 1/20 0.34
CRACR2A Q9BSW2 2/20 0.34
EPHX2 P34913 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SORT1 Q99523 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9116142 0.85 DHODH (0.39) DHODHTAS1R3TAS1R1TAS1R2MEN1
SCHEMBL9117324 0.85 DHODH (0.36) DHODHTAS1R3TAS1R1TAS1R2MEN1
SCHEMBL8492849 0.85 DHODH (0.36) DHODHTAS1R3TAS1R1TAS1R2MEN1
SCHEMBL8492875 0.84 DHODH (0.35) DHODHTAS1R3TAS1R1TAS1R2MEN1
SCHEMBL8491585 0.83 DHODH (0.35) DHODHTAS1R3TAS1R1TAS1R2MEN1
SCHEMBL9116542 0.82 PRKDC (0.38) DHODHTAS1R3TAS1R1TAS1R2PDE2A
SCHEMBL9116511 0.82 DHODH (0.34) DHODHTAS1R3TAS1R1TAS1R2MEN1
SCHEMBL7558174 0.82 DHODH (0.36) DHODHMEN1KMT2ACRHR1HPGD
SCHEMBL7575360 0.82 DHODH (0.34) DHODHTAS1R3TAS1R1TAS1R2MEN1
SCHEMBL9116643 0.81 PDE2A (0.35) DHODHTAS1R3TAS1R1TAS1R2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995022904-A1 PESTICIDAL METHOD RHONE POULENC AGROCHIMIE (FR) 1995-08-31 WO disclosed