Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 19/20 | 0.55 |
| ▸ | TDO2 | P48775 | 18/20 | 0.55 |
| ▸ | IDO2 | Q6ZQW0 | 10/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222336 | 0.93 | TDO2 (0.63) | IDO1TDO2IDO2MEN1APAF1 | |
| SCHEMBL30639070 | 0.85 | IDO1 (0.58) | IDO1TDO2IDO2MEN1APAF1 | |
| SCHEMBL26856109 | 0.84 | IDO1 (0.58) | IDO1TDO2IDO2MEN1APAF1 | |
| SCHEMBL26863142 | 0.81 | IDO1 (0.54) | IDO1TDO2IDO2MEN1APAF1 | |
| SCHEMBL26863157 | 0.81 | IDO1 (0.54) | IDO1TDO2IDO2MEN1APAF1 | |
| SCHEMBL30639128 | 0.81 | IDO1 (0.50) | IDO1TDO2IDO2MEN1APAF1 | |
| SCHEMBL26855987 | 0.80 | IDO1 (0.67) | IDO1TDO2IDO2MEN1APAF1 | |
| SCHEMBL4585634 | 0.79 | IDO1 (0.80) | IDO1TDO2IDO2MEN1APAF1 | |
| SCHEMBL26614098 | 0.79 | IDO1 (0.67) | IDO1TDO2IDO2MEN1APAF1 | |
| SCHEMBL31382842 | 0.79 | TDO2 (0.46) | IDO1TDO2IDO2MEN1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441955-A | Tuberculosis | PATHOGENESIS CORPORATION (US) | 1995-08-15 | — | — | US | disclosed |
| WO-1995013807-A1 | INDOLO[2,1-b]QUINAZOLINE-6,12-DIONE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | PATHOGENESIS CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |