Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TOP2A | P11388 | 2/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL11546910 | 0.85 | MAPT (0.49) | MAPTMEN1KMT2ATDP1POLB | |
| Hydrochloric Acid SCHEMBL11550657 | 0.82 | MAPT (0.54) | MAPTMEN1KMT2ATDP1POLB | |
| SCHEMBL9113715 | 0.81 | TOP2A (0.57) | MEN1KMT2ATDP1TOP2ATOP2B | |
| Iodide SCHEMBL11546914 | 0.78 | MAPT (0.49) | MAPTMEN1KMT2ATDP1POLB | |
| SCHEMBL29409289 | 0.71 | MAPT (1.00) | MAPTMEN1KMT2ATDP1POLB | |
| SCHEMBL737722 | 0.71 | MAPT (1.00) | MAPTMEN1KMT2ATDP1POLB | |
| SCHEMBL18985916 | 0.69 | MAPT (0.58) | MAPTMEN1KMT2ATDP1POLB | |
| SCHEMBL28920609 | 0.69 | MAPT (0.50) | MAPTMEN1KMT2ATDP1POLB | |
| SCHEMBL17476786 | 0.68 | MAPT (0.53) | MAPTMEN1KMT2ATDP1POLB | |
| SCHEMBL10771288 | 0.68 | MAPT (0.49) | MAPTMEN1KMT2ATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995008540-A1 | BIS(AMIDINOBENZIMIDAZOLYL)ALKANES AS ANTIVIRAL AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-03-30 | — | — | WO | disclosed |