Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.58 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 2/20 | 0.53 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115467 | 1.00 | KRAS (0.58) | KRASTNFRSF1APTPN1F3CXCL12 | |
| SCHEMBL9114991 | 0.90 | KRAS (0.68) | KRASTNFRSF1APTPN1F3CXCL12 | |
| SCHEMBL9114998 | 0.90 | KRAS (0.68) | KRASTNFRSF1APTPN1F3CXCL12 | |
| SCHEMBL9113078 | 0.89 | PTPN1 (0.53) | KRASTNFRSF1APTPN1MAOBMAPT | |
| SCHEMBL9113085 | 0.89 | PTPN1 (0.53) | KRASTNFRSF1APTPN1MAOBMAPT | |
| SCHEMBL9115084 | 0.89 | MAPT (0.59) | PTPN1MAOBMAPTALDH1A1KMT2A | |
| SCHEMBL9115244 | 0.89 | PTPN1 (0.51) | PTPN1F3CXCL12MAOBMAPT | |
| SCHEMBL9115255 | 0.89 | PTPN1 (0.51) | PTPN1F3CXCL12MAOBMAPT | |
| SCHEMBL9241047 | 0.87 | ABCG2 (0.55) | PTPN1MAOBMAPTALDH1A1KDM4E | |
| SCHEMBL9115673 | 0.86 | PTPN1 (0.56) | TNFRSF1APTPN1MAOBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |