Biphenyl

Biphenyl

SCHEMBL9116003

CC[K].c1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
SMN1; SMN2 Q16637 3/20 0.46
MAPT P10636 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
SLC22A2 O15244 1/20 0.46
SLC22A1 O15245 1/20 0.46
SLC22A3 O75751 1/20 0.46
SLC6A4 P31645 1/20 0.46
TP53 P04637 1/20 0.45
TAAR1 Q96RJ0 3/20 0.44
HPGD P15428 2/20 0.43
CYP1A2 P05177 2/20 0.43
MAPK1 P28482 1/20 0.43
CYP3A4 P08684 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NOTUM Q6P988 1/20 0.43
MMP3 P08254 1/20 0.43
BCL2L1 Q07817 1/20 0.43
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL323849 0.86 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2MAPTL3MBTL1SLC22A2
Biphenyl SCHEMBL967556 0.83 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2MAPTL3MBTL1SLC22A2
Biphenyl SCHEMBL7625521 0.82 ALDH1A1 (0.75) ALDH1A1SMN1; SMN2MAPTSLC22A2SLC22A1
Biphenyl SCHEMBL8855942 0.80 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2MAPTL3MBTL1SLC22A2
Biphenyl SCHEMBL8328818 0.80 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2MAPTL3MBTL1SLC22A2
Biphenyl SCHEMBL7043290 0.80 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2MAPTL3MBTL1SLC22A2
Biphenyl SCHEMBL4840882 0.80 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2MAPTL3MBTL1SLC22A2
Biphenyl SCHEMBL8310031 0.80 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2MAPTL3MBTL1SLC22A2
Biphenyl SCHEMBL22500791 0.80 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2MAPTL3MBTL1SLC22A2
Biphenyl SCHEMBL4606121 0.80 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2MAPTL3MBTL1SLC22A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0663892-A1 THINNERS FOR AQUEOUS SUSPENSIONS OF MINERAL PARTICLES AND HYDRAULIC BINDER PASTES. CHRYSO SA (FR) 1995-07-26 EP disclosed
WO-1994008913-A1 THINNERS FOR AQUEOUS SUSPENSIONS OF MINERAL PARTICLES AND HYDRAULIC BINDER PASTES CHRYSO (S.A.) (FR) 1994-04-28 WO disclosed