Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15635084 | 0.85 | TSHR (0.44) | TSHRTDP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL17863583 | 0.85 | TSHR (0.48) | TSHRSLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL8709152 | 0.79 | TSHR (0.33) | TSHRTDP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6811532 | 0.79 | TSHR (0.33) | TSHRTDP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7011964 | 0.77 | TSHR (0.48) | TSHRTDP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1014269 | 0.75 | TSHR (0.39) | TSHRTDP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL31365655 | 0.75 | HTT (0.33) | TSHRSLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL10389317 | 0.74 | EPHX2 (0.43) | CSNK1E | |
| SCHEMBL10389319 | 0.74 | EPHX2 (0.43) | CSNK1E | |
| SCHEMBL9141093 | 0.74 | HDAC2 (0.52) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019373-A1 | ANTIBODIES SPECIFIC FOR D-MYO-INOSITOL 1,4,5-TRISPHOSPHATE | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS (US) | 1995-07-20 | — | — | WO | disclosed |
| US-5393912-A | D-myo-inositol 1,4,5-trisphosphate analogues | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS (US) | 1995-02-28 | — | — | US | disclosed |