Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CCR2 | P41597 | 5/20 | 0.60 |
| ▸ | CCR1 | P32246 | 1/20 | 0.60 |
| ▸ | GRIK1 | P39086 | 6/20 | 0.57 |
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12204331 | 0.85 | CA12 (0.67) | NPC1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5594972 | 0.84 | DHODH (0.75) | NPC1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9117619 | 0.81 | TRPV1 (0.60) | NPC1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6823242 | 0.78 | GRIK1 (0.75) | NPC1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9118124 | 0.78 | GRIK1 (0.61) | MEN1KMT2ACCR2CCR1GRIK1 | |
| SCHEMBL4548131 | 0.76 | KMT2A (1.00) | NPC1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5171084 | 0.75 | KMT2A (0.58) | NPC1MEN1KMT2ASMN1; SMN2GRIK1 | |
| SCHEMBL4105004 | 0.74 | CNR1 (0.74) | NPC1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11054644 | 0.74 | CNR1 (0.74) | NPC1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8109117 | 0.74 | MEN1 (0.64) | NPC1MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033460-A1 | ANTI-INFLAMMATORY COUMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | claimed |
| US-5447957-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORP. (US) | 1995-09-05 | — | — | US | claimed |
| WO-1995033460-A1 | ANTI-INFLAMMATORY COUMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |
| US-5447957-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORP. (US) | 1995-09-05 | — | — | US | disclosed |