Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 9/20 | 0.58 |
| ▸ | NOS1 | P29475 | 5/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | TK1 | P04183 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PAH | P00439 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235225 | 0.99 | HPRT1 (0.57) | HPRT1NOS1NOS3NOS2TK1 | |
| SCHEMBL3836268 | 0.83 | HPRT1 (0.61) | HPRT1NOS1NOS3NOS2TK1 | |
| SCHEMBL9739844 | 0.82 | HPRT1 (0.60) | HPRT1NOS1NOS3NOS2USP2 | |
| SCHEMBL146837 | 0.82 | HPRT1 (0.58) | HPRT1NOS1TK1USP2CASP7 | |
| SCHEMBL571646 | 0.82 | HPRT1 (0.60) | HPRT1NOS1TK1CYP1A2 | |
| SCHEMBL7192798 | 0.81 | HPRT1 (0.57) | HPRT1NOS1TK1USP2CASP7 | |
| Water SCHEMBL10414024 | 0.81 | HPRT1 (0.57) | HPRT1NOS1TK1USP2CASP7 | |
| SCHEMBL571080 | 0.81 | HPRT1 (0.60) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL7197096 | 0.81 | HPRT1 (0.57) | HPRT1NOS1TK1USP2CASP7 | |
| SCHEMBL10920053 | 0.80 | HPRT1 (0.56) | HPRT1NOS1USP2CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995022330-A1 | ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1995-08-24 | — | — | WO | disclosed |