Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15766010 | 0.95 | GRM5 (0.39) | GRM5HRH3 | |
| SCHEMBL15766073 | 0.80 | GRM5 (0.42) | GRM5HRH3 | |
| SCHEMBL3992638 | 0.73 | CHRNA1 (0.41) | GRM5HRH3 | |
| SCHEMBL3820096 | 0.72 | CHRNA1 (0.43) | GRM5HRH3 | |
| SCHEMBL22787406 | 0.71 | — | — | |
| SCHEMBL15641646 | 0.71 | GRM5 (0.61) | GRM5 | |
| SCHEMBL28350055 | 0.70 | LMNA (0.46) | GRM5 | |
| SCHEMBL9115267 | 0.70 | LMNA (0.49) | GRM5 | |
| SCHEMBL15766015 | 0.70 | KDM4E (0.43) | GRM5 | |
| SCHEMBL4368776 | 0.69 | SLC6A4 (0.40) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446203-A | Synthesis of haloenones and aryl or alkyl substituted enones or alkenes | NEW YORK UNIVERSITY (US) | 1995-08-29 | — | — | US | disclosed |
| EP-0656878-A4 | SYNTHESIS OF HALOENONES AND ARYL OR ALKYL SUBSTITUTED ENONES OR ALKENES. | — | 1995-07-05 | — | — | EP | disclosed |
| EP-0656878-A1 | SYNTHESIS OF HALOENONES AND ARYL OR ALKYL SUBSTITUTED ENONES OR ALKENES | NEW YORK UNIVERSITY (US) | 1995-06-14 | — | — | EP | disclosed |
| WO-1994005617-A1 | SYNTHESIS OF HALOENONES AND ARYL OR ALKYL SUBSTITUTED ENONES OR ALKENES | NEW YORK UNIVERSITY (US) | 1994-03-17 | — | — | WO | disclosed |