Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 18/20 | 0.74 |
| ▸ | PPP3CA | Q08209 | 3/20 | 0.74 |
| ▸ | FKBP4 | Q02790 | 2/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.74 |
| ▸ | MLNR | O43193 | 1/20 | 0.74 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.74 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.74 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.74 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.74 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.74 |
| ▸ | HTR2A | P28223 | 1/20 | 0.74 |
| ▸ | HTR2B | P41595 | 1/20 | 0.74 |
| ▸ | MTOR | P42345 | 1/20 | 0.74 |
| ▸ | FKBP1B | P68106 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.74 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920318 | 0.97 | FKBP1A (0.75) | FKBP1APPP3CAFKBP4ABCB11ADORA3 | |
| SCHEMBL8923145 | 0.95 | FKBP1A (0.73) | FKBP1APPP3CAFKBP4ABCB11ADORA3 | |
| SCHEMBL8911904 | 0.95 | FKBP1A (0.71) | FKBP1APPP3CAFKBP4ABCB11ADORA3 | |
| SCHEMBL9118135 | 0.95 | FKBP1A (0.80) | FKBP1APPP3CAFKBP4ABCB11ADORA3 | |
| SCHEMBL9118172 | 0.94 | FKBP1A (0.80) | FKBP1APPP3CAFKBP4ABCB11ADORA3 | |
| SCHEMBL9118103 | 0.94 | FKBP1A (0.73) | FKBP1APPP3CAFKBP4ABCB11ADORA3 | |
| SCHEMBL8919529 | 0.93 | FKBP1A (0.74) | FKBP1APPP3CAFKBP4ABCB11ADORA3 | |
| SCHEMBL9117925 | 0.92 | FKBP1A (0.83) | FKBP1APPP3CAFKBP4ABCB11ADORA3 | |
| SCHEMBL8921673 | 0.92 | FKBP1A (0.72) | FKBP1APPP3CAFKBP4ABCB11ADORA3 | |
| SCHEMBL9116803 | 0.92 | FKBP1A (0.81) | FKBP1APPP3CAFKBP4ABCB11ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995035299-A1 | ARYL, ALKYL, ALKENYL AND ALKYNYLMACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY | MERCK & CO., INC. (US) | 1995-12-28 | — | — | WO | claimed |
| WO-1995035299-A1 | ARYL, ALKYL, ALKENYL AND ALKYNYLMACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY | MERCK & CO., INC. (US) | 1995-12-28 | — | — | WO | disclosed |