Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 8/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9117162 | 0.92 | KCNH2 (0.55) | KCNH2DRD4CYP2J2 | |
| SCHEMBL9116913 | 0.90 | HSD11B1 (0.56) | — | |
| SCHEMBL9116197 | 0.90 | HSD11B1 (0.55) | — | |
| SCHEMBL9114251 | 0.86 | KCNH2 (0.58) | KCNH2DRD4 | |
| SCHEMBL9242355 | 0.84 | MAPT (0.49) | DRD4CYP2J2 | |
| SCHEMBL9117470 | 0.83 | MAPT (0.55) | KCNH2 | |
| SCHEMBL9117363 | 0.83 | SMN1; SMN2 (0.56) | — | |
| SCHEMBL9117377 | 0.82 | SMN1; SMN2 (0.55) | — | |
| SCHEMBL9115903 | 0.82 | SMN1; SMN2 (0.55) | — | |
| SCHEMBL9236308 | 0.82 | SMN1; SMN2 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025731-A1 | NOVEL 3-(φ-(4-BENZOYLPIPERIDINO)ALKYL)-4H-BENZOPYRAN-4-ONES, PREPARATION AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1995-09-28 | — | — | WO | disclosed |