SCHEMBL9116576

SCHEMBL9116576

CC(=O)OCCC(CCOS(C)(=O)=O)(COC(C)=O)COC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
TSHR P16473 2/20 0.38
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.38
USP2 O75604 1/20 0.38
MMP9 P14780 1/20 0.38
ALOX15 P16050 1/20 0.38
CHRM5 P08912 2/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33
PGR P06401 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
HTR1A P08908 1/20 0.33
CHRNB2 P17787 1/20 0.33
TBXA2R P21731 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9115523 0.78 ALDH1A1 (0.39) ALDH1A1TSHRLMNAALOX15CHRM5
SCHEMBL2169178 0.77 ALDH1A1 (0.50) ALDH1A1TSHRLMNAKDM4EUSP2
SCHEMBL4690035 0.74 ALDH1A1 (0.39) ALDH1A1TSHRLMNAALOX15CHRM5
SCHEMBL1960864 0.74 ALDH1A1 (0.65) ALDH1A1TSHRLMNAKDM4EUSP2
SCHEMBL2167190 0.74 ALDH1A1 (0.58) ALDH1A1TSHRLMNAKDM4EUSP2
SCHEMBL1961059 0.72 ALDH1A1 (0.54) ALDH1A1TSHRLMNAKDM4EUSP2
SCHEMBL2166882 0.72 TSHR (0.62) ALDH1A1TSHRLMNAKDM4EUSP2
SCHEMBL2168830 0.72 TSHR (0.62) ALDH1A1TSHRLMNAKDM4EUSP2
SCHEMBL13642334 0.70 ALDH1A1 (0.48) ALDH1A1TSHRLMNAKDM4EUSP2
SCHEMBL309351 0.70 ALDH1A1 (0.50) ALDH1A1TSHRLMNAALOX15CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995022330-A1 ANTIVIRAL AGENTS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1995-08-24 WO disclosed