Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 3/20 | 0.46 |
| ▸ | FNTB | P49356 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.46 |
| ▸ | SQLE | Q14534 | 1/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908593 | 0.83 | KDM4E (0.55) | KDM4EATMKMT2APOLBFNTA | |
| SCHEMBL8908580 | 0.83 | KDM4E (0.55) | KDM4EATMKMT2APOLBFNTA | |
| SCHEMBL8908589 | 0.83 | KDM4E (0.55) | KDM4EATMKMT2APOLBFNTA | |
| SCHEMBL8771800 | 0.82 | GGPS1 (0.50) | FNTAFNTBGGPS1 | |
| SCHEMBL8771729 | 0.82 | KDM4E (0.43) | KDM4EATMKMT2APOLBFNTA | |
| SCHEMBL794370 | 0.81 | KDM4E (0.60) | KDM4EATMKMT2APOLBFNTA | |
| SCHEMBL794369 | 0.81 | KDM4E (0.60) | KDM4EATMKMT2APOLBFNTA | |
| SCHEMBL8771720 | 0.80 | KDM4E (0.44) | KDM4EATMKMT2APOLBFNTA | |
| SCHEMBL8771732 | 0.80 | KDM4E (0.44) | KDM4EATMKMT2APOLBFNTA | |
| SCHEMBL8771619 | 0.79 | GGPS1 (0.47) | KDM4EATMFNTAFNTBGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686159-A1 | FARNESYL:PROTEIN TRANSFERASE INHIBITORS AS ANTICANCER AGENTS | MERRELL DOW PHARMA (US) | 1995-12-13 | — | — | EP | disclosed |
| WO-1994019357-A1 | FARNESYL:PROTEIN TRANSFERASE INHIBITORS AS ANTICANCER AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-09-01 | — | — | WO | disclosed |