SCHEMBL9116835

SCHEMBL9116835

Cc1ccc2ncc(CCN)n2c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 1/20 0.46
KDM4E B2RXH2 1/20 0.43
GLA P06280 1/20 0.43
GAA P10253 1/20 0.43
POLB P06746 1/20 0.42
TGFBR1 P36897 1/20 0.40
PRMT5 O14744 1/20 0.39
WDR77 Q9BQA1 1/20 0.39
RXFP1 Q9HBX9 2/20 0.37
TAAR1 Q96RJ0 2/20 0.37
CYP2A6 P11509 1/20 0.37
HRH1 P35367 1/20 0.37
HRH4 Q9H3N8 1/20 0.37
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
MAP3K14 Q99558 1/20 0.35
USP7 Q93009 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21083369 0.86 TGFBR1 (0.51) CYP1A2CYP2C9KDM4EGLAGAA
SCHEMBL22300408 0.81 CYP1A2 (0.50) CYP1A2CYP2C9KDM4EGLAGAA
SCHEMBL20593123 0.80 MAP3K14 (0.44) GAAPOLBTGFBR1TAAR1HRH1
SCHEMBL5657000 0.79 CYP1A2 (0.49) CYP1A2CYP2C9KDM4EGLAGAA
SCHEMBL17815897 0.77 POLB (0.69) CYP1A2CYP2C9KDM4EGLAGAA
SCHEMBL20125088 0.75 CYP1A2 (0.49) CYP1A2CYP2C9KDM4EGLAGAA
SCHEMBL9234953 0.75 DNMT1 (0.46) KDM4EGLAGAAPRMT5WDR77
SCHEMBL5655359 0.75 CYP1A2 (0.40) CYP1A2CYP2C9KDM4EGLAGAA
SCHEMBL21083341 0.73 CYP1A2 (0.53) CYP1A2CYP2C9KDM4EGLAGAA
SCHEMBL20125127 0.73 CYP1A2 (0.53) CYP1A2CYP2C9KDM4EGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995018817-A1 NOVEL ADENOSINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME LABORATOIRES UPSA (FR) 1995-07-13 WO disclosed