Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5311542 | 0.88 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3LSSTAAR1 | |
| SCHEMBL8354603 | 0.81 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3EPHX2OPRM1 | |
| SCHEMBL5646483 | 0.80 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3EPHX2 | |
| SCHEMBL11111686 | 0.80 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3EPHX2 | |
| Hydrochloric Acid SCHEMBL11105518 | 0.79 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3EPHX2 | |
| Hydrochloric Acid SCHEMBL6477899 | 0.79 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3EPHX2 | |
| SCHEMBL9116606 | 0.79 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3EPHX2LSS | |
| SCHEMBL14347875 | 0.78 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3EPHX2 | |
| SCHEMBL5645141 | 0.77 | SLC6A3 (0.46) | SLC6A4SLC6A2SLC6A3DPP4 | |
| SCHEMBL11634132 | 0.74 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995021615-A1 | USE OF ARYLCYCLOBUTYLALKYLAMINES FOR THE TREATMENT OF SEIZURES AND NEUROLOGICAL DISORDERS | KNOLL AG (DE) | 1995-08-17 | — | — | WO | claimed |
| WO-1995021615-A1 | USE OF ARYLCYCLOBUTYLALKYLAMINES FOR THE TREATMENT OF SEIZURES AND NEUROLOGICAL DISORDERS | KNOLL AG (DE) | 1995-08-17 | — | — | WO | disclosed |