Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 19/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058281 | 0.87 | CA2 (0.49) | CA2CA4CA1CA9 | |
| SCHEMBL9058179 | 0.85 | CA2 (0.42) | CA2CA4CA1CA9CA12 | |
| SCHEMBL9058335 | 0.85 | CA2 (0.47) | CA2CA4CA1CA9HRH3 | |
| SCHEMBL9058019 | 0.83 | CA2 (0.47) | CA2CA4CA1CA9CA12 | |
| SCHEMBL9058844 | 0.83 | CA2 (0.40) | CA2CA4CA1CA9CA12 | |
| SCHEMBL9057317 | 0.81 | CA2 (0.45) | CA2CA4CA1CA9 | |
| SCHEMBL9057348 | 0.81 | CA2 (0.49) | CA2CA4CA1CA9CA12 | |
| SCHEMBL9058838 | 0.80 | CA2 (0.49) | CA2CA4 | |
| SCHEMBL9057893 | 0.80 | CA2 (0.50) | CA2CA4CA1CA9CA12 | |
| SCHEMBL9061894 | 0.80 | CA2 (0.45) | CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019981-A1 | THIENOTHIAZINE SULFONAMIDE DERIVATIVES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS CARBONIC ANHYDRASE INHIBITORS | ALCON LABORATORIES, INC. (US) | 1995-07-27 | — | — | WO | disclosed |