Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118415 | 0.95 | PTGS2 (0.56) | PTGS2PTGS1SMN1; SMN2ABCC4ABCB11 | |
| SCHEMBL9119288 | 0.95 | PTGS2 (0.56) | PTGS2PTGS1SMN1; SMN2ABCC4ABCB11 | |
| SCHEMBL9117061 | 0.86 | PTGS2 (0.49) | PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL9119888 | 0.85 | PTGS2 (0.63) | PTGS2PTGS1ABCC4ABCB11PDE4D | |
| SCHEMBL9118925 | 0.84 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL9115937 | 0.83 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL9119972 | 0.83 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL8973804 | 0.82 | PTGS2 (0.42) | PTGS2PTGS1SMN1; SMN2ABCC4ABCB11 | |
| SCHEMBL9115408 | 0.82 | PTGS2 (0.47) | PTGS2PTGS1SMN1; SMN2POLB | |
| SCHEMBL9116138 | 0.82 | PTGS2 (0.47) | PTGS2PTGS1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030652-A1 | SUBSTITUTED SPIRODIENES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-11-16 | — | — | WO | claimed |