SCHEMBL9117348

SCHEMBL9117348

CCN(CC)c1ccc2c(c1)Oc1cc(C)c(N(c3ccccc3)c3ccccc3)cc1C2c1ccccc1C(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.40
SMN1; SMN2 Q16637 7/20 0.40
LMNA P02545 6/20 0.40
NPSR1 Q6W5P4 5/20 0.40
L3MBTL1 Q9Y468 4/20 0.40
NPC1 O15118 4/20 0.40
TDP1 Q9NUW8 2/20 0.40
ALDH1A1 P00352 5/20 0.39
HSD17B10 Q99714 4/20 0.39
MAPK1 P28482 4/20 0.39
RAB9A P51151 2/20 0.39
ALOX15 P16050 1/20 0.39
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
CYP2C9 P11712 2/20 0.37
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
TSHR P16473 2/20 0.36
POLB P06746 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9113560 0.95 MAPT (0.40) MAPTSMN1; SMN2LMNANPSR1L3MBTL1
SCHEMBL9116454 0.94 MAPT (0.41) MAPTSMN1; SMN2LMNANPSR1L3MBTL1
SCHEMBL9115561 0.91 MAPT (0.40) MAPTSMN1; SMN2LMNANPSR1L3MBTL1
SCHEMBL7194575 0.91 MAPT (0.44) MAPTSMN1; SMN2LMNANPSR1L3MBTL1
SCHEMBL9114905 0.90 MAPT (0.40) MAPTSMN1; SMN2LMNANPSR1L3MBTL1
SCHEMBL9116680 0.90 MAPT (0.46) MAPTSMN1; SMN2LMNANPSR1L3MBTL1
SCHEMBL9116133 0.89 MAPT (0.39) MAPTSMN1; SMN2LMNANPSR1L3MBTL1
SCHEMBL9116506 0.89 MAPT (0.42) MAPTSMN1; SMN2LMNANPSR1L3MBTL1
SCHEMBL3890180 0.88 MAPT (0.48) MAPTSMN1; SMN2LMNANPSR1L3MBTL1
SCHEMBL9115816 0.88 MAPT (0.42) MAPTSMN1; SMN2LMNANPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5389489-A Support having coating layer with microcapsules containing leuco dye and photooxidizing agent, reducing agent FUJI PHOTO FILM CO., LTD. (JP) 1995-02-14 US disclosed