Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8391027 | 0.98 | CYP2C9 (0.47) | MAPTSMN1; SMN2NPSR1LMNANPC1 | |
| SCHEMBL9176269 | 0.95 | MAPT (0.47) | MAPTSMN1; SMN2NPSR1LMNANPC1 | |
| SCHEMBL12923595 | 0.95 | MAPT (0.45) | MAPTSMN1; SMN2NPSR1LMNANPC1 | |
| SCHEMBL7194575 | 0.94 | MAPT (0.44) | MAPTSMN1; SMN2NPSR1LMNANPC1 | |
| SCHEMBL7186463 | 0.91 | MAPT (0.42) | MAPTSMN1; SMN2NPSR1LMNANPC1 | |
| SCHEMBL9115816 | 0.91 | MAPT (0.42) | MAPTSMN1; SMN2NPSR1LMNANPC1 | |
| SCHEMBL9171441 | 0.91 | MAPT (0.42) | MAPTSMN1; SMN2NPSR1LMNANPC1 | |
| SCHEMBL7185259 | 0.90 | MAPT (0.41) | MAPTSMN1; SMN2NPSR1LMNANPC1 | |
| SCHEMBL10676478 | 0.90 | MAOB (0.47) | MAPTSMN1; SMN2NPSR1LMNANPC1 | |
| SCHEMBL9114656 | 0.89 | MAPT (0.43) | MAPTSMN1; SMN2NPSR1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9636363-B2 | Halogenated rhodamine derivatives and applications thereof | KIADIS PHARMA CANADA INC. (CA) | 2017-05-02 | — | — | US | disclosed |
| US-20140314720-A1 | HALOGENATED RHODAMINE DERIVATIVES AND APPLICATIONS THEREOF | THERATECHNOLOGIES, INC. (CA) | 2014-10-23 | — | — | US | disclosed |
| US-20090176869-A1 | Halogenated Rhodamine Derivatives and Applications Thereof | CELMED BIOSCIENCE INC. (CA) | 2009-07-09 | — | — | US | disclosed |
| EP-1765592-B1 | METHOD FOR MAKING NEGATIVE-WORKING HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2009-01-28 | — | — | EP | disclosed |
| US-20080311524-A1 | Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor | AGFA GRAPHICS N.V. (BE) | 2008-12-18 | — | — | US | disclosed |
| EP-1614541-A2 | Method of making a lithographic printing plate. | Agfa-Gevaert (BE) | 2006-01-11 | — | — | EP | disclosed |
| EP-0239868-B1 | PHOTOCHROMIC SYSTEM, LAYER PREPARED THEREOF AND ITS USE | BASF Aktiengesellschaft (DE) | 1989-12-27 | — | — | EP | disclosed |
| US-4857438-A | Photochromic system and layers produced therewith | BASF AKTIENGESELLSCHAFT (DE) | 1989-08-15 | — | — | US | disclosed |
| EP-0239868-A1 | Photochromic system, layer prepared thereof and its use | BASF Aktiengesellschaft (DE) | 1987-10-07 | — | — | EP | disclosed |
| US-4332884-A | USING A DIOXIME CHELATING AGENT | RICOH CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |
| US-4315068-A | CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS | RICOH CO., LTD. (JP) | 1982-02-09 | — | — | US | disclosed |
| US-4306014-A | AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM | RICOH CO., LTD. (JP) | 1981-12-15 | — | — | US | disclosed |
| US-4251619-A | Process for forming photo-polymeric image | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1981-02-17 | — | — | US | disclosed |
| US-4139390-A | Presensitized printing plate having a print-out image | EASTMAN KODAK COMPANY (US) | 1979-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176869-A1 | Halogenated Rhodamine Derivatives and Applications Thereof | H1-10, HRH3, RPLP0 | MAPT 4884/4885SMN1; SMN2 4810/4885NPSR1 785/4885 |
| US-20140314720-A1 | HALOGENATED RHODAMINE DERIVATIVES AND APPLICATIONS THEREOF | RARA, DDC, RARB | MAPT 3160/4885SMN1; SMN2 4637/4885NPSR1 3915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.