⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28351231 | 1.00 | — | — | |
| SCHEMBL5687039 | 0.88 | CA1 (0.35) | — | |
| SCHEMBL18381234 | 0.79 | SHBG (0.46) | — | |
| SCHEMBL19576324 | 0.79 | — | — | |
| SCHEMBL3480995 | 0.78 | — | — | |
| SCHEMBL9320793 | 0.77 | — | — | |
| SCHEMBL22364331 | 0.77 | — | — | |
| SCHEMBL22088568 | 0.77 | SHBG (0.37) | — | |
| SCHEMBL28465309 | 0.77 | CA1 (0.42) | — | |
| SCHEMBL17538639 | 0.77 | SHBG (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995031471-A1 | 19,11β BRIDGED 18-NOR STEROIDS, PROCESS FOR PRODUCING THEM, MEDICAMENTS CONTAINING SAID STEROIDS AND THEIR USE IN THE PRODUCTION OF MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-11-23 | — | — | WO | disclosed |
| EP-0338065-B1 | DERIVATIVES OF 19-NORPROGESTERONE, THEIR PREPARATION AND THEIR USE | THERAMEX (MC) | 1994-01-26 | — | — | EP | disclosed |
| EP-0338065-A1 | DERIVATIVES OF 19-NORPROGESTERONE, THEIR PREPARATION AND THEIR USE | LABORATOIRE THERAMEX (MC) | 1989-10-25 | — | — | EP | disclosed |
| WO-1989003839-A1 | DERIVATIVES OF 19-NORPROGESTERONE, THEIR PREPARATION AND THEIR USE | LABORATOIRE THERAMEX S.A. (MC) | 1989-05-05 | — | — | WO | disclosed |