SCHEMBL9117779

SCHEMBL9117779

OCCCCCCCCCCc1c(O)cccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
ALDH1A1 P00352 1/20 0.40
TAAR1 Q96RJ0 2/20 0.39
AKR1B1 P15121 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
CNR1 P21554 2/20 0.35
CNR2 P34972 2/20 0.35
CA2 P00918 1/20 0.35
TBXAS1 P24557 2/20 0.34
CFTR P13569 2/20 0.33
LMNA P02545 1/20 0.33
PGR P06401 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAOA P21397 1/20 0.33
TBXA2R P21731 1/20 0.33
MAPK1 P28482 1/20 0.33
AVPR2 P30518 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL137678 0.92 TSHR (0.45) TSHRALDH1A1TAAR1AKR1B1SMN1; SMN2
SCHEMBL5294145 0.86 TAAR1 (0.52) TSHRTAAR1AKR1B1SMN1; SMN2TBXAS1
SCHEMBL19866382 0.84 TSHR (0.48) TSHRALDH1A1TAAR1AKR1B1SMN1; SMN2
SCHEMBL28929217 0.84 CA2 (0.38) ALDH1A1SMN1; SMN2CNR1CNR2CA2
SCHEMBL30695756 0.84 BID (0.47) ALDH1A1SMN1; SMN2TBXAS1CFTRLMNA
SCHEMBL27967827 0.84 BID (0.47) ALDH1A1SMN1; SMN2TBXAS1CFTRLMNA
SCHEMBL14158501 0.84 BID (0.47) ALDH1A1SMN1; SMN2TBXAS1CFTRLMNA
SCHEMBL15995365 0.84 BID (0.47) ALDH1A1SMN1; SMN2TBXAS1CFTRLMNA
SCHEMBL14158807 0.81 CFTR (0.48) TSHRALDH1A1SMN1; SMN2CFTRMAPT
SCHEMBL1926900 0.80 TAAR1 (0.54) TSHRTAAR1AKR1B1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995031425-A1 NOVEL CO-ORDINATED METAL/BORON COMPOUNDS AS BIOCIDES, THEIR METHODS OF SYNTHESIS, THEIR USE AND THEIR FORMULATION MAYNARD NIGEL PAUL (NZ) 1995-11-23 WO disclosed