Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9117082 | 0.98 | PTGS2 (0.50) | PTGS2PTGS1ALOX5APMTOR | |
| SCHEMBL9117211 | 0.95 | PTGS2 (0.55) | PTGS2PTGS1ALOX5APMTOR | |
| SCHEMBL9115530 | 0.93 | PTGS2 (0.47) | PTGS2PTGS1ALOX5APMTOR | |
| SCHEMBL9242413 | 0.91 | PTGS2 (0.47) | PTGS2PTGS1ALOX5AP | |
| SCHEMBL9118694 | 0.90 | PTGS2 (0.38) | PTGS2PTGS1ALOX5APMTOR | |
| SCHEMBL9118379 | 0.88 | PTGS2 (0.52) | PTGS2PTGS1MTOR | |
| SCHEMBL9119878 | 0.88 | PTGS2 (0.38) | PTGS2PTGS1ALOX5APMTOR | |
| SCHEMBL9118479 | 0.87 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL9117275 | 0.85 | PTGS2 (0.38) | PTGS2PTGS1ALOX5APMTOR | |
| SCHEMBL9242350 | 0.85 | PTGS2 (0.42) | PTGS2PTGS1ALOX5APMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030652-A1 | SUBSTITUTED SPIRODIENES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-11-16 | — | — | WO | disclosed |