Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022308 | 0.81 | P2RX7 (0.58) | P2RX7KDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL29651292 | 0.80 | KDM4E (0.63) | P2RX7KDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL17210751 | 0.80 | P2RX7 (0.52) | P2RX7KDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL71547 | 0.80 | KDM4E (0.63) | P2RX7KDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL23830166 | 0.80 | P2RX7 (0.66) | P2RX7KDM4ETDP1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1646832 | 0.79 | KDM4E (0.61) | P2RX7KDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL9507784 | 0.79 | KDM4E (0.61) | P2RX7KDM4ETDP1ALDH1A1MAPT | |
| Iodide SCHEMBL10567955 | 0.79 | KDM4E (0.61) | P2RX7KDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL27612979 | 0.79 | KDM4E (0.61) | P2RX7KDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL7715770 | 0.79 | KDM4E (0.61) | P2RX7KDM4ETDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |