Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 3/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | GLA | P06280 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | HTR3A | P46098 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116887 | 1.00 | HTR4 (0.76) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL9119676 | 1.00 | HTR4 (0.76) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL9116964 | 0.90 | HTR4 (0.76) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL9118349 | 0.88 | HTR4 (0.78) | HTR4CYP3A4GLA | |
| SCHEMBL2579561 | 0.86 | HTR4 (1.00) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL29386039 | 0.86 | HTR4 (1.00) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL22532550 | 0.85 | HTR4 (0.98) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL9117893 | 0.83 | HTR4 (0.78) | HTR4CYP3A4GLA | |
| SCHEMBL9117654 | 0.82 | HTR4 (0.79) | HTR4CYP3A4GLA | |
| SCHEMBL2943813 | 0.81 | HTR4 (0.71) | HTR4CYP3A4GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025100-A1 | USE OF 4-AMINO-5-CHLORO-2-METHOXYBENZOIC ESTERS AS 5-HT4 AGONISTS | SANOFI (FR) | 1995-09-21 | — | — | WO | claimed |
| WO-1995025100-A1 | USE OF 4-AMINO-5-CHLORO-2-METHOXYBENZOIC ESTERS AS 5-HT4 AGONISTS | SANOFI (FR) | 1995-09-21 | — | — | WO | disclosed |