Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21612061 | 0.82 | MAPT (0.46) | LMNANPSR1KMT2AMEN1MAPT | |
| SCHEMBL5271074 | 0.81 | MAPT (0.53) | LMNAKMT2AMEN1MAPTGAA | |
| SCHEMBL20598163 | 0.78 | MAPT (0.42) | LMNANPSR1KMT2AMEN1MAPT | |
| SCHEMBL5727280 | 0.78 | MAPT (0.42) | LMNANPSR1KMT2AMEN1MAPT | |
| SCHEMBL6345016 | 0.77 | MAPT (0.41) | LMNANPSR1KMT2AMEN1MAPT | |
| SCHEMBL29980612 | 0.76 | KMT2A (0.55) | LMNANPSR1KMT2AMEN1MAPT | |
| SCHEMBL12483037 | 0.75 | MAPT (0.50) | LMNAKMT2AMEN1MAPTGAA | |
| SCHEMBL9117738 | 0.74 | GPR35 (0.48) | ALDH1A1HPGDGSK3BKDM4ETSHR | |
| SCHEMBL6345019 | 0.73 | KMT2A (0.41) | LMNANPSR1KMT2AMEN1MAPT | |
| SCHEMBL28907995 | 0.72 | MAPT (0.65) | LMNAKMT2AMEN1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025105-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD (GB) | 1995-09-21 | — | — | WO | disclosed |