Sulfuric Acid

Sulfuric Acid

SCHEMBL9118744

CCCCCCCCCc1c(N)cccc1O.CCCCCCCCCc1c(N)cccc1O.O=S(=O)(O)O

nearest known ligand 0.46

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Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 3/20 0.46
MCL1 Q07820 3/20 0.46
KAT8 Q9H7Z6 3/20 0.46
BCL2L1 Q07817 2/20 0.46
BAK1 Q16611 2/20 0.46
EP300 Q09472 2/20 0.46
KAT5 Q92993 2/20 0.46
SAE1 Q9UBE0 2/20 0.46
PPARG P37231 1/20 0.46
PPARA Q07869 1/20 0.46
KAT2A Q92830 1/20 0.46
KAT2B Q92831 1/20 0.46
MAPT P10636 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
ATM Q13315 1/20 0.43
ELANE P08246 2/20 0.42
CTSG P08311 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11482542 0.92 BID (0.47) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL28035905 0.92 BID (0.47) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL11250153 0.92 BID (0.47) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL8379228 0.92 BID (0.47) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL11486890 0.92 BID (0.47) BIDMCL1KAT8BCL2L1BAK1
Formaldehyde SCHEMBL10667790 0.91 BID (0.48) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL1568283 0.91 BID (0.45) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL1026540 0.85 HTT (0.46) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL4837086 0.84 BID (0.51) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL1115550 0.82 TTR (0.46) MEN1ALDH1A1KMT2ACA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104053697-A New reactive surfactants for emulsion polymerization, pigment dispersion, and UV coatings ETHOX CHEMICALS LLC 2014-09-17 CN disclosed
WO-1995032255-A1 WATERBORNE LACQUERS COMPRISING SELF-STABILIZED LATTICES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-11-30 WO disclosed
US-5374614-A With controlled amount of lower aliphatic alcohols and mixture of nonionic, anionic, cationic and amphoteric surfactants QUEST INTERNATIONAL B.V. (NL) 1994-12-20 US disclosed
EP-0571677-A1 Aqueous parfume oil microemulsions UNILEVER PLC (GB) 1993-12-01 EP disclosed