Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3639817 | 0.76 | KDM4E (0.42) | KDM4ELMNAHTTTDP1NPC1 | |
| SCHEMBL24350766 | 0.70 | KDM4E (0.38) | TP53CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7540735 | 0.69 | NPC1 (0.45) | KDM4ESMN1; SMN2NPC1L3MBTL1RAB9A | |
| SCHEMBL292870 | 0.68 | CHRM2 (0.40) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL11031282 | 0.67 | KDM4E (0.42) | TP53CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10426369 | 0.63 | KDM4E (0.50) | TP53CHRM2CHRM4CHRM5CHRM1 | |
| Dipyridyl SCHEMBL29120981 | 0.62 | KDM4E (0.70) | TP53KDM4ELMNAHIF1ACCR1 | |
| Dipyridyl SCHEMBL5787557 | 0.61 | KDM4E (0.78) | TP53KDM4ELMNAHIF1ACCR1 | |
| SCHEMBL30694104 | 0.61 | TP53 (1.00) | TP53KDM4ELMNAHIF1ACCR1 | |
| SCHEMBL2852298 | 0.61 | TP53 (1.00) | TP53KDM4ELMNAHIF1ACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389663-A | Fungicides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |