Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4252990 | 0.97 | MAPT (0.46) | MAPTKDM4EALDH1A1POLBANPEP | |
| SCHEMBL4209117 | 0.97 | MAPT (0.46) | MAPTKDM4EALDH1A1POLBANPEP | |
| SCHEMBL9119907 | 0.95 | MAPT (0.44) | MAPTKDM4EALDH1A1POLBANPEP | |
| SCHEMBL9282036 | 0.95 | MAPT (0.44) | MAPTKDM4EALDH1A1POLBANPEP | |
| SCHEMBL23532238 | 0.89 | MAPT (0.52) | MAPTKDM4EALDH1A1POLBANPEP | |
| SCHEMBL336769 | 0.89 | MAPT (0.52) | MAPTKDM4EALDH1A1POLBANPEP | |
| SCHEMBL3966649 | 0.89 | MAPT (0.52) | MAPTKDM4EALDH1A1POLBANPEP | |
| SCHEMBL31222541 | 0.89 | MAPT (0.50) | MAPTKDM4EALDH1A1POLBANPEP | |
| SCHEMBL4254925 | 0.82 | MAPT (0.46) | MAPTKDM4EALDH1A1POLBANPEP | |
| SCHEMBL19473215 | 0.82 | MAPT (0.58) | MAPTKDM4EALDH1A1POLBANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995020353-A1 | FUNCTIONALIZED AZA-BIMACROCYCLIC LIGANDS FOR IMAGING APPLICATIONS | MALLINCKRODT MEDICAL, INC. (US) | 1995-08-03 | — | — | WO | disclosed |