SCHEMBL336769

SCHEMBL336769

O=P(O)(O)CN1CCN(CP(=O)(O)O)CCN(CP(=O)(O)O)CCN(CP(=O)(O)O)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.52
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
ANPEP P15144 2/20 0.38
ERAP2 Q6P179 1/20 0.38
MMP2 P08253 1/20 0.37
THRB P10828 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
FDPS P14324 3/20 0.35
TYMS P04818 1/20 0.33
PKM P14618 1/20 0.32
RAB9A P51151 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3966649 1.00 MAPT (0.52) MAPTKDM4EALDH1A1POLBANPEP
SCHEMBL23532238 1.00 MAPT (0.52) MAPTKDM4EALDH1A1POLBANPEP
SCHEMBL4254925 0.92 MAPT (0.46) MAPTKDM4EALDH1A1POLBANPEP
SCHEMBL4209117 0.92 MAPT (0.46) MAPTKDM4EALDH1A1POLBANPEP
SCHEMBL4252990 0.92 MAPT (0.46) MAPTKDM4EALDH1A1POLBANPEP
SCHEMBL19473215 0.92 MAPT (0.58) MAPTKDM4EALDH1A1POLBANPEP
SCHEMBL9119907 0.89 MAPT (0.44) MAPTKDM4EALDH1A1POLBANPEP
SCHEMBL9119009 0.89 MAPT (0.44) MAPTKDM4EALDH1A1POLBANPEP
SCHEMBL2243964 0.89 MAPT (0.44) MAPTKDM4EALDH1A1POLBANPEP
SCHEMBL9282036 0.89 MAPT (0.44) MAPTKDM4EALDH1A1POLBANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 753 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4211146-B1 SYNTHETIC CYCLIC PEPTIDE MIMETICS UNIV BAR ILAN (IL) 2026-05-20 EP claimed
WO-2026099626-A1 METHODS AND SYSTEMS FOR MANUFACTURING RADIOPHARMACEUTICALS NOVARTIS AG (CH) 2026-05-15 WO claimed
US-12616760-B2 Synthetic cyclic peptide mimetics BAR ILAN UNIVERSITY (IL) 2026-05-05 US claimed
EP-4719486-A1 CONJUGATES AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
EP-4719498-A1 RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
US-12576168-B2 Peptide PET/SPECT probes specific to oncoproteins in tumor extracellular matrix CASE WESTERN RESERVE UNIVERSITY (US) 2026-03-17 US claimed
EP-4705295-A2 MULTIFUNCTIONAL COMPOUND CORE FOR ACTIVE AGENTS AND USES THEREOF The University of North Carolina at Chapel Hill (US) 2026-03-11 EP claimed
EP-4694940-A1 STEAP2-TARGETED COMPOUNDS AND USE THEREOF Astrazeneca AB (SE) 2026-02-18 EP claimed
US-20260021211-A1 Dual mode radiotracer and -therapeutics UNIV MUENCHEN TECH (DE) 2026-01-22 US claimed
US-20250387522-A1 PSMA TARGETED PET AND FLUORESCENCE IMAGING COMPOUNDS UNIV CASE WESTERN RESERVE (US) 2025-12-25 US claimed
US-20190175750-A1 COMPOSITION AND METHOD FOR MODIFYING POLYPEPTIDES ADVANCED PROTEOME THERAPEUTICS INC. 2019-06-13 US claimed
EP-2453927-B1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES UNIV DENMARK TECH DTU (DK) 2019-05-15 EP claimed
EP-2651447-B1 ENTRAPMENT OF RADIONUCLIDES IN NANOPARTICLE COMPOSITIONS UNIV DENMARK TECH DTU (DK) 2018-08-29 EP claimed
US-20170296684-A1 RADIOPHARMACEUTICAL CONJUGATE UNIVERSITY OF CAPE TOWN (ZA) 2017-10-19 US claimed
US-20160158392-A1 Entrapment of Radionuclides in Nanoparticle Compositions RIGSHOSPITALET (DK) 2016-06-09 US claimed
US-9226984-B2 Entrapment of radionuclides in nanoparticle compositions Technical University of Denmark and Rigshospitalet (DK) 2016-01-05 US claimed
US-20150202336-A1 Loading Technique for Preparing Radionuclide Containing Nanoparticles RIGSHOSPITALET (DK) 2015-07-23 US claimed
US-8920775-B2 Loading technique for preparing radionuclide containing nanoparticles TECHNICAL UNIVERSITY OF DENMARK (DK) 2014-12-30 US claimed
US-20130251630-A1 Entrapment of Radionuclides in Nanoparticle Compositions RIGSHOSPITALET (DK) 2013-09-26 US claimed
US-20120213698-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES RIGSHOSPITALET (DK) 2012-08-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616760-B2 Synthetic cyclic peptide mimetics TPX2, IAPP, HAX1 MAPT 1283/4885KDM4E 2888/4885ALDH1A1 4698/4885
US-20150202336-A1 Loading Technique for Preparing Radionuclide Containing Nanoparticles LIPG, NPC1L1, CD47 MAPT 4367/4885KDM4E 2122/4885ALDH1A1 4468/4885
US-12576168-B2 Peptide PET/SPECT probes specific to oncoproteins in tumor extracellular matrix FN1, INHA, EDNRB MAPT 2982/4885KDM4E 2560/4885ALDH1A1 4553/4885
US-20250387522-A1 PSMA TARGETED PET AND FLUORESCENCE IMAGING COMPOUNDS PSMA3, PSMA1, PSMA7 MAPT 670/4885KDM4E 206/4885ALDH1A1 1438/4885
US-20260021211-A1 Dual mode radiotracer and -therapeutics FOLH1, SLC19A1, KLK3 MAPT 3073/4885KDM4E 3927/4885ALDH1A1 2663/4885
US-20190175750-A1 COMPOSITION AND METHOD FOR MODIFYING POLYPEPTIDES PTMS, SRMS, ACP1 MAPT 592/4885KDM4E 3594/4885ALDH1A1 3789/4885
US-20120213698-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES LIPG, NPC1L1, CD47 MAPT 4367/4885KDM4E 2122/4885ALDH1A1 4468/4885
US-20170296684-A1 RADIOPHARMACEUTICAL CONJUGATE FOLH1, EPRS1, FOLR1 MAPT 3460/4885KDM4E 2174/4885ALDH1A1 1889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.